Chloramphenicol
The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of Sildenafil by affecting the patient hepatic and intestinal enzyme metabolism.
Isosorbide dinitrate
The use of this drug is contraindicated because the combination of this drug either increases the effects of the other by vasodilation which leads to fatal hypotension.
Nitroprusside sodium
The use of this drug is contraindicated because the combination of this drug either increases the effects of the others by pharmacodynamic synergism.
Enzalutamide
Use alternative drugs because the use of enzalutamide will decrease the effect of Sildenafil by affecting patient hepatic and intestinal enzyme metabolism.
Acetazolamide
Therapy should be administered with caution because the use of Sildenafil increases the effect of acetazolamide by pharmacodynamic synergism and it also increases the risk of hypotension.
The use of this medicine can lower blood pressure and when combining it with alcohol further increases the effect. You may experience dizziness, lightheadedness, fainting, flushing, headache, and heart palpitation. Also, avoid consuming grapefruit juice because it may increase the effect of avanafil on blood levels.
Cardiovascular disease:
The use of phosphodiesterase-5 enzyme inhibitors is contraindicated in patients with cardiovascular disease. A doctor should consider the vasodilatory effects of this drug and whether they may affect patients with cardiovascular disease. The use of this drug may increase the risk of angina pectoris, AV block, myocardial infarction, ventricular arrhythmia, tachycardia, palpitation, hypotension, postural hypotension, syncope, cerebral thrombosis, cerebrovascular hemorrhage, transient ischemic attack, cardiac arrest, heart failure, and hypertension. These events can occur during or after sexual activity.
Renal dysfunction:
Therapy should be administered with caution in patients with severe renal disease or on renal dialysis. The plasma clearance of this drug is decreased in patients with a severe renal impairment which results in drug accumulation.
Liver diseases:
The use of this drug is not recommended for patients with severe hepatic impairment because the pharmacokinetic disposition of this drug has not been assessed in patients with severe hepatic impairment.
Addictive (IDs or other drugs)The FDA has provided a black box warning for the presence of these drug interactions. The FDA offers a black box warning for the presence of these drug interactions in patients aged 5-44 years. The use of this drug may increase blood pressure and when combined with alcohol further increases the effect.
Interaction(s) physicalxiety/ DepressionAceclofenac | Alcohol |
You may experience dizziness, lightheadedness, fainting, flushing, headache, dizziness, or fainting.
Tadalafil, commonly known by its brand name Cialis, is a medication that belongs to the class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. It works by relaxing the blood vessels in the penis, allowing increased blood flow during sexual stimulation. This increase in blood flow can result in an erection, allowing for a firmer and longer-lasting erection. Tadalafil's effectiveness can be attributed to its mechanism of action in regulating blood flow in the penis. Its active ingredient, tadalafil, is a selective phosphodiesterase type 5 (PDE5) inhibitor that works by inhibiting an enzyme called cyclic guanosine monophosphate (cGMP) that plays a role in erectile function. Tadalafil works by increasing the levels of cGMP in the penis, which relaxes the blood vessels, allowing increased blood flow during sexual stimulation.
Tadalafil is available in tablet form, and should be taken 30 to 60 minutes before anticipated sexual activity. The typical starting dose of tadalafil is 20mg, taken approximately 30 minutes before sexual activity. The dosage can be adjusted based on individual response and tolerability. It's important to follow your healthcare provider's instructions when taking tadalafil, as it may not be suitable for everyone.
Common side effects of tadalafil may include headache, flushing, and nasal congestion. More serious side effects are rare but may include vision changes such as blue tinge or blurred vision. If you experience any severe side effects or have any concerns about your health, seek immediate medical attention.
When taking tadalafil, it's important to be aware of potential interactions with other medications and supplements. Inform your healthcare provider of all medications and supplements you are taking to avoid any potential drug interactions. If you have any liver or kidney problems, inform your healthcare provider about all forms of supplements and herbs you are taking.
Tadalafil is stored at room temperature, away from moisture and light. Disposal of tadalafil should be done after the expiration date mentioned by your healthcare provider.
Appropriate Disposal of tadalafilIndividuals who have taken tadalafil should be aware of the risks associated with this medication. It is important to follow the instructions given by the healthcare provider and to complete the full course of treatment. Never take tadalafil without consulting your healthcare provider.
Safe Usage of tadalafilSome people may experience mild to moderate side effects while taking tadalafil. Common side effects include headache, flushing, nasal congestion, indigestion, and upset stomach. If these side effects persist or worsen, seek medical attention promptly. In rare cases, tadalafil may cause more serious side effects such as sudden vision or hearing loss or prolonged erection (priapism). If you experience any unusual symptoms while taking tadalafil, seek medical attention immediately.
Serious Side EffectsIndividuals who have been diagnosed with a rare form of benign prostatic hyperplasia (BPH) may be at risk for the development of cardiovascular events. If you have any of the above conditions, avoid taking tadalafil, as it may increase the risk of serious side effects.
Individuals with a history of high blood pressure, high cholesterol, or diabetes should avoid taking tadalafil. It is important to inform your healthcare provider about all medications you are currently taking to prevent potential risks and interactions.As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. Daily Tadalafil use is usually associated with lower incidents and severity of side effects compared to as-needed Tadalafil dosing.
Most common Tadalafil side effects
Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:
For a complete list of possible side effects,.
Possible drug interactions
Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.
On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.
For a complete list of possible drug interactions,.
Other important safety information
Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.
After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.
Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or healthcare provider.
Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
See also:
Erectile dysfunction
Even though Tadalafil has been shown to be effective for many patients, Tadalafil is not intended to replace or enhance the daily use of prescribed medications. Tadalafil is intended for single-dose use only. Patients with specific medical conditions, such as high or low blood pressure, heart problems, low blood pressure, or those taking certain medications, may require different doses of Tadalafil. Always consult with a healthcare provider before taking any dose of Tadalafil.
Tadalafil is not approved for use in treating erectile dysfunction.
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Tadalafil is used to treat erectile dysfunction (ED) in men.
Tadalafil Tadalafil Tablets contain the active ingredient tadalafil. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor and works by relaxing the blood vessels in your penis. This allows more blood flow to the penis and helps you achieve and maintain an erection. Tadalafil has been proven to be effective in treating ED. Tadalafil works by increasing blood flow to the penis and helping you achieve and maintain an erection when sexually stimulated.
Tadalafil is available in tablet form and is taken orally with or without food. The recommended dose of tadalafil is 20 mg taken once daily. The dose may be adjusted based on the severity of the condition being treated.
The recommended dose of tadalafil is usually 20 mg taken once daily.
The dosage of tadalafil 20 mg should be reduced to 20 mg based on the severity of the condition being treated.